Friday 6 May 2011

2011 Research Profile

Title: Dr    

Family/Surname/Last Name: Basten                        

First Names:    Graham            

Current Job title:    Associate Head of School                        

Faculty/Institute: HLS

Department/School: Allied Health Sciences

DMU Research Centre:

  • Research Group affiliations: Biomedical and Environmental (AHS)
  • Food and Nutrition (HLS)
  • Grand Challenges Ageing LLHW advisory group (DMU)
  • Transdisciplinary (DMU)


 


 

Contact Details


 

Email: gbasten@dmu.ac.uk


 

Website: http://www.dmu.ac.uk/research/hls/staff/basten.jsp

Twitter: http://twitter.com/grahambasten

Academic Blog: http://isothiocyanates.blogspot.com/

Research Blog: http://grahambastenresearch.blogspot.com/


 


 

Personal Profile: (list or provide an overview containing as many key words about your work/area as possible):


 

"Nutrition: Cells to Communities"

  • Clinical Nutrition
    • Folate
    • Glucosinolates
    • Blood test results / pathology
    • CVD (homocysteine and vascular tone) and cancer risk (uracil misincorporation)
    • Cell culture, clinical chemistry, molecular biology, vascular tone physiology (exercise).
    • Added value, product reformulation, fortification, supplementation and functional foods


     

  • Social Nutrition
    • Use of validated Food diaries and nutrient analysis
    • Access to food and food policy
    • Community and school meals


 


 

Externally Funded Research Grants Information

Project title, Funding agency, type of project, start date, end date, role in project, collaborators


 

  • £40k from 2008 to date
  • I co-wrote bids for the 3rd sector East Midlands charity as part of the RIF project and received over £40k from Sport Relief, One Nottingham and the Big Lottery to allow the community group to develop a healthy cookbook and address health and wellness.
  • 2011 Royal Society Partnership Fund with Crompton School £3,000
  • 2011 Big Lottery Fund Awards for All with OSCAR Nottingham £11,495
  • 2010 One Nottingham £4,830 with OSCAR Nottingham
  • 2010 Comic Relief - core funding for Sickle Cell sufferer support about £28k over 2 years with OSCAR Nottingham


 


 

Internally Funded Research Project Information

Project title, Funding source, type of project, Start date, end date, role in project, collaborators


 

  • £17k from 2008 to date


 

  1. DMU RIF: £6k Healthy Building Design (PI), 2009-2010, AHS (HLS), Art and Design and IESD.
  2. DMU RIF: £3k Food and Nutrition (PI), 2009-2010, AHS, NHS, 3rd sector charity, local government.
  3. DMU Teacher Fellow: £2k Technology and learning, (PI) 2010-2011
  4. DMU Antioxidant Project, £2k, AHS, Pharmacy and Nursing (I), 2008-2009
  5. DMU TQEF £2k: Moodle vs Blackboard, AHS, (I) 2009
  6. DMU RITA £2K Virtual Analytical Laboratory, AHS, (I), 2008-2009


 

Consultancy/External Income Generation Information:

Area of expertise, previous consultancies undertaken, currently available Y/N, companies worked with.

  • Understanding blood test results
  • Pepsi Co: Working on their wellness programme by reformulating products to contain less sugar and salt.
  • One Nottingham / Nottingham City Council / Marmot to investigate how social housing, school meals and nutrition effects social aspiration, health and wellness.


 


 


 

'Outputs' produced since January 2008 not yet included in DORA


 

  • Comparative effects of a 16-week folate-rich mixed diet versus folic acid intervention and influence of MTHFR C677T genotype on folate status and homocysteine in a 2-centre randomised placebo-controlled study
    Maria J King1, Anthony Lynn2, Caroline A Wolfe1, Graham P Basten2, Gavin Willis3, Anthony J Wright1, Margo E Barker2, Hilary J Powers2 and Paul M Finglas1 Molecular Nutrition and Food Research


 

Conference Attendance

Title, dates, location, title of contribution, authors, type of contribution


 

Honours & Awards

Name of honour / award, month conferred, year conferred, reason conferred

  • DMU Teacher Fellow, August 2010, Pedagogy Research.


 

Membership of Professional Associations & Societies

Association Name, period start, period end, Description


 

  • Member of IBMS 2007-date
  • Member of Phytochemical Society of Europe 2007-date
  • Member of Nutrition Society 2000-2008
  • Fellow of Higher Education Academy


 


 

Impact case studies

Examples of evidence of the 'Impact' of research e.g. references to reviews/articles in main stream media, examples of feedback from users, exhibition attendance figures


 

Evidence of research esteem (RAE)

Graham P Basten joined DMU May 2007 as Senior Lecturer in Clinical Chemistry - Biomedical Sciences, after working at the Medical Schools at the Universities of Sheffield and Nottingham for nearly 7 years. He is now Associate Head of School for Allied Health Sciences.

GP Basten is currently establishing his research group at DMU. He is internationally known for his work on how micronutrients modulate the pathophysiology of disease in the context of early-stage biomarkers in non-invasive surrogate tissue. Immediately prior to DMU he worked with Prof HJ Powers (University of Sheffield) in collaboration with Paul Finglas (Institute of Food Research) on the relationship between folate status and biomarkers of cardiovascular disease, cancer and health. The intervention work looked at food intervention vs supplementation using food diaries, 24 hour recall and clinical makers. In collaboration with Dr SJ Duthie (Rowett Research Institute) he validated biomarkers of DNA instability, showed that folate supplementation elicited a significant reduction in uracil misincorporation in healthy people, and developed an automated method to measure folate in lymphocytes and buccal cells. With Prof SA Watson (University of Nottingham) he showed that hyperplastic polyps have elevated levels of pre-cancerous biomarkers compared with normal resection colorectal samples. In a European Union project co-ordinated by Prof IT Johnson and Prof G Williamson (Institute of Food Research) he investigated the induction of phase II detoxification enzymes (i.e. human bilirubin UDP-glucuronosyl transferase) and apoptosis by glucosinolate derived isothiocyantes. With Prof AJ Knox (Nottingham City Hospital) he elucidated how cGMP modulates nitric oxide levels in asthma and cystic fibrosis patients. He maintains strong links with the collaborators listed above.


 

Evidence of esteem:

He has been invited to speak at a number of international and national meetings (i.e. 6th Winter Research Conference on Free Radicals, France (2003), the 15th International Symposium on Regulatory Peptides, Toulouse, France (2004), the Nutrition Society Meeting 2005 and helped to organise the Nutrition Society Meeting 2001, and the Sheffield Teaching Hospitals Trust Cancer Research Away Day). He was co-author on a comprehensive review of folate, DNA stability and colo-rectal neoplasia (Proc. Nutr. Soc. 2004;63(4):571-8). Media dissemination to BBC Radio Sheffield, local and national press, and worked with the current premiership squad of Sheffield United Football Club. Prior to joining DMU he has co-written several successful external grants (i.e. Food Standards Agency (FSA) 460K, completed 8 months ahead of schedule, World Cancer Research Fund (WCRF) 240K) and submitted grants with novel collaborations (i.e. National Institutes of Health USA, collaboration with Anderson Cancer Centre, USA, and the Royal Society Pump Priming Award, collaboration with the Dept. of Architecture, University of Sheffield). Based on previous work, submissions and collaborations he anticipates potential funding for future research at DMU from the FSA, WCRF, CORE, EU and BBSRC.

Thursday 5 May 2011

DMU/OSCAR Food Manual

OSCAR Nottingham and Dr Graham Basten (DMU) have written a Food Manual with exciting recipes and a whole range of hints, tips and information about healthy and economic shopping, cooking and eating. If you are interested in purchasing a copy, please contact us: http://oscarnottingham.org/Index.aspx

The urgent news is that we are launching the Food Manual on Friday 6th May - this is to gather opinion from the public about holistic health including diet and nutrition and there will be health stalls and some speakers including a local GP. It's very short notice but if you can drop in it would be great.

It is from 10 am to 4 pm at the Elohim Community Centre on the Wells Road, near Hendon Rise (parking off Hendon Rise), Nottingham

Wednesday 9 February 2011

Ismaili Nutrition Launch

Brilliant networking at the Midlands Launch of the Aga Khan Health Board's Ismaili Nutrition Centre.

This work closely replicates the nutrition work I am doing at DMU, we have been collecting data on the nutritional profile of foods from South Asian, African, Caribbean and undergraduate cohorts in the East Midlands.

Wednesday 26 January 2011

Sickle Cell Meeting

Great discussion between Graham Basten and Sharon Cox. Talking about sickle cell research at DMU, SCOOTER LSHTM, Tanzania and KEMRI. Discussed some exciting potential research and training potential.

Tuesday 9 November 2010

Research activity

• Royal Society Partnership Grant with Crompton View School
• Art and Design Project to look at stress
• Member of transdiscipline group at DMU
• Member of DMU Connected Communities Bid Team,

More information to follow...!

Wednesday 29 September 2010

School Foods: Healthy Children, Healthy Minds

I recently attended the School Foods: Healthy Children, Healthy Minds event at the Royal Society.

There were some excellent speakers on this difficult and interesting topic