New paper published:
Blood folate status and expression of proteins involved in immune function, inflammation, and coagulation: biochemical and proteomic changes in the plasma of humans in response to long-term synthetic folic acid supplementation.
Monday, 7 June 2010
The prevalence of Fusobacterium necrophorum in persistent sore throat swabs: a screening method that is hard to swallow?
The prevalence of Fusobacterium necrophorum in persistent sore throat swabs: a screening method that is hard to swallow?
Submitted for publication in the British Journal of Biomedical Science as a Biomedical Science in Brief Article
Submitted for publication in the British Journal of Biomedical Science as a Biomedical Science in Brief Article
Revolving Investment Fund (RIF)
Revolving Investment Fund (RIF)
I have secured two RIF grants from DMU (<£20k), one to look at healthy building design and one to look at food and nutrition.
Healthy building design
Introduction:
To allow research workshops and activities to discuss the effect of the NHS / Medical building design and engineering on acute and long-term health, and will be encompassed in two themes.
Theme one examines the effect of the clinical built environment on reliable data collection. NHS strategies Point of Care testing, Choices, and creation of primary care holders encourages more clinical measurements to be taken in a variety of settings. Co-driving this is modern technology which allows sensitive clinical measures to be made in non-conventional settings (for example at home or in supermarket car parks). However, the effect of the built environment on these measures is unclear.
Theme two examines the long-term health effects of poor building design and engineering using the latest research from cross disciplines.
Food and nutrition
Introduction:
The food and nutrition cluster at HLS faculty has an established and evolving international reputation for academic research in food and human nutrition. The cluster offers dynamic research across a wide cross-section of activities from pure, applied, NHS, e-learning and social sciences.
1) This project will identify key areas and groupings within the cluster and foster a food and nutrition research culture conducive to grant submissions
2) Specifically, it will allow further development and collaborative workshops and meetings between the NHS, Graham Basten and Simon Dyson to address the issue of clinical, nutritional and social aspects of Sickle Cell Disease.
I have secured two RIF grants from DMU (<£20k), one to look at healthy building design and one to look at food and nutrition.
Healthy building design
Introduction:
To allow research workshops and activities to discuss the effect of the NHS / Medical building design and engineering on acute and long-term health, and will be encompassed in two themes.
Theme one examines the effect of the clinical built environment on reliable data collection. NHS strategies Point of Care testing, Choices, and creation of primary care holders encourages more clinical measurements to be taken in a variety of settings. Co-driving this is modern technology which allows sensitive clinical measures to be made in non-conventional settings (for example at home or in supermarket car parks). However, the effect of the built environment on these measures is unclear.
Theme two examines the long-term health effects of poor building design and engineering using the latest research from cross disciplines.
Food and nutrition
Introduction:
The food and nutrition cluster at HLS faculty has an established and evolving international reputation for academic research in food and human nutrition. The cluster offers dynamic research across a wide cross-section of activities from pure, applied, NHS, e-learning and social sciences.
1) This project will identify key areas and groupings within the cluster and foster a food and nutrition research culture conducive to grant submissions
2) Specifically, it will allow further development and collaborative workshops and meetings between the NHS, Graham Basten and Simon Dyson to address the issue of clinical, nutritional and social aspects of Sickle Cell Disease.
Revolving Investment Fund (RIF)
I have secured two RIF grants from DMU (<£20k), one to look at healthy building design and one to look at food and nutrition.
Healthy building design
Introduction:
Food and nutrition
Introduction:
Healthy building design
Introduction:
To allow research workshops and activities to discuss the effect of the NHS / Medical building design and engineering on acute and long-term health, and will be encompassed in two themes.
Theme one examines the effect of the clinical built environment on reliable data collection. NHS strategies Point of Care testing, Choices, and creation of primary care holders encourages more clinical measurements to be taken in a variety of settings. Co-driving this is modern technology which allows sensitive clinical measures to be made in non-conventional settings (for example at home or in supermarket car parks). However, the effect of the built environment on these measures is unclear.
Food and nutrition
Introduction:
The food and nutrition cluster at HLS faculty has an established and evolving international reputation for academic research in food and human nutrition. The cluster offers dynamic research across a wide cross-section of activities from pure, applied, NHS, e-learning and social sciences.
1) This project will identify key areas and groupings within the cluster and foster a food and nutrition research culture conducive to grant submissions
2) Specifically, it will allow further development and collaborative workshops and meetings between the NHS, Graham Basten and Simon Dyson to address the issue of clinical, nutritional and social aspects of Sickle Cell Disease.
My research at DMU
The following summarises my research activity as part of the strategy of the faculty of health and life sciences and the School of Allied Health Sciences:
Qualifications: PhD, BSc (Hons. Sand.)
Research Interests
- Diet and health based human intervention trials
- Sickle Cell Anaemia and Diet
- Ethnicity and the health paradox
- Diet, pregnancy and infant health
- Folic Acid: Cancer and Cardiovascular Disease – clinical blood results, biomarkers and physiological measurements
- Induction of phase-II detoxification enzymes by cruciferous vegetables: Glucosinolates, super broccoli and cancer
- Clinical chemistry method development
Recent Publications
- Basten, G.P., Duthie, S.J., Pirie, L., Hill, M.H., Powers, H.J, Sensitivity of markers of DNA stability and DNA repair activity to folate supplementation in healthy volunteers. British Journal Of Cancer 2006, 94, 1942-1947.
- Basten, G.P., Hill, M.H., Duthie, S.J, Powers, H.J., Effect of Folic Acid Supplementation on the Folate Status of Buccal Mucosa and Lymphocytes, Cancer Epidemiol Biomarkers 2004; 13, 7.
- Narayanan, S., McConnell, J., Little, J., Sharp, L., Piyathilake, C.J., Powers, H., Basten, G., Duthie, S.J., Associations between Two common variants C677T and A1298C in the Methylenetrahydrofolate Reductase Gene and Measures of Folate Metabolism and DNA Stability (Strand Breaks, Misincorporated Uracil and DNA Methylation Status) in Human Lympocytes In Vivo, Cancer Epidemiol Biomarkers & Prevention, 2004, 13, 1436-1443
- Basten, G.P., Y, Bao., Williamson, G., Sulforaphane and its glutathione conjugate but not sulforaphane nitrile induce UDP-glucuronosyl transferase (UGT1A1) and glutathione transferase (GSTA1) in cultured cells. Carcinogenesis 2002 Vol. 23, 8, 1399-1404.
Projects
- Assessment of the dietary intake of ethnic populations in Leicester using 24 hour recall and 7 day food diaries.
- Food fortification vs supplements and the nutrient contents of various food and drinks.
- Antioxidant capacity of generic ethnic ingredients and dishes.
- Role of phytochemicals in cancer and heart disease.
Esteem/Professional Contribution
- Fellow of the Higher Education Academy
- Senior Fellow Award Panel Judge for the HEA
- Grant review expert for the BBSRC AgriFood Committee
- Member of Health and Wellbeing Nutrition Advisory panel for PEPSICO
- University Representative for the Society of Biology
- Member of The Institute of Biomedical Science
- Member of The Phytochemical Society of Europe
Subscribe to:
Posts (Atom)